Volume 10, Number 3 (13 2004)                   Back to this Issue | Back to browse issues page


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Pakgohar M, Mehran A, Salehi Sour Moghi M, Akhondzadeh S, Ahmadi M. Comparison of hypericum perforatum and placebo in treatment of physical symptoms of premenstrual syndrome. Hayat. 2004; 10 (3) :31-37
URL: http://hayat.tums.ac.ir/article-1-256-en.html

Abstract:   (5450 Views)

Introduction: A variety of maladies, sometimes disabling, beset many ovulatory women in a recurrent manner during the luteal phase of each ovarian cycle. These problems can deteriorate interpersonal relationships and/or interfere with normal activities of life. Present research was performed to evaluate effects of hypericum perforatum for treatment of physical symptoms of premenstrual syndrome.

Materials and Methods: This study was a randomized, double-blind, placebo-controlled, parallel group compassion study performed over two menstrual cycles on student of Tehran University of Medical Sciences and Tehran University. Volunteers underwent a preliminary screening interview, completed Beck questionnaire as a screening test for depression and attended a medical screening visit before being diagnosed as having premenstrual syndrome. Participants administrated hypericum or placebo, 30 drops BD, for two complete cycles. Premenstrual symptoms were evaluated by a daily symptom report form. Data analysis performed by Chi square, Fisher exact, Wilcoxon and t tests.

Results: Premenstrual daily hypericum caused a significant improvement in mean daily score of severity of premenstrual problems compared to placebo (p<0.05). Premenstrual administration of hypericum, 30 drop BD, showed significant advantage over placebo for physical disorders (%49, p=000).

Conclusion: Daily premenstrual administration of hypericum perforatum treats physical symptoms of premenstrual syndrome. It seems that hypericum perforatum can improve symptoms of premenstrual syndrome.

Full-Text [PDF 153 kb]   (1701 Downloads)    
Type of Study: Research | Subject: Nursing Care
Published: 2013/08/11 | ePublished: 2013/08/11

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